Tomás Alvira was born on January 17, 1906, in Villanueva de Gállego, Zaragoza, Spain. He pursued studies in Chemical Sciences, eventually earning a doctorate and establishing himself as a respected researcher with the Spanish National Research Council (CSIC). In 1939, he began teaching Natural Sciences at the prestigious Ramiro de Maeztu Institute in Madrid, where he was known for his innovative educational approach, emphasizing the concept of the "Living Classroom."

During the Spanish Civil War, in September 1937, Tomás met St. Josemaría Escrivá, the founder of Opus Dei. This encounter profoundly influenced him, leading to his incorporation as a Supernumerary member of Opus Dei on February 15, 1947. Tomás embraced the organization's message of seeking holiness through everyday professional and family life, becoming the first married member to do so.

Tomás married Paquita Domínguez Susín on June 16, 1939, and together they had nine children. Their household was a testament to Christian values, often described as a "bright and cheerful home," reflecting St. Josemaría's vision. Tomás's dedication to faith and family left a lasting impact on those around him. He passed away on May 7, 1992, in Madrid. Recognizing their exemplary lives, the Archdiocese of Madrid opened causes for the canonization of both Tomás and Paquita, highlighting their unwavering commitment to faith, family, and the principles of Opus Dei.